What are Growth Factors?
Growth factors are scientifically identified, biologically active, small proteins that regulate normal cell growth, cell development and function, and ultimately cell death. Growth factors are active within the body at very low physiological concentrations that range from nanogram levels (10-9 molar, or .0000000001) and lower. This is exponentially below any pharmacological level. Due to the key physiological roles of growth factors in growth and development in the body and brain, defects in growth factor regulation are hypothesized to be involved with many diseases.4 (Patton et al. 1989). Higher than normal concentrations of growth factors, or inappropriately activated growth factors contribute to pathophysiological (abnormal) cell signaling 6 (Bellavite & Signorini 1995). Cells which have been stressed or damaged may also have affected cell receptor sites at which growth factors stimulate activation. A challenge is to address this issue.
Growth factors, such as fibroblast growth factor-2 (FGF-2), insulin-like growth factor-1 (IGF-1), platelet-derived growth factor-BB (PDGFBB) and human growth hormone (hGH) participate in developmental stages of growth. During several important developmental stages, changes occur that are fundamental for health. Examples of such events are: nerve cell development and specialization, protection against toxins, detoxification processes, neuronal survival, neuronal outgrowth and nutritional uptake.
Growth Factors and Viruses Compete for Gene Regulation
Growth factors (also known by neurologists as neuropeptides and by immunologists as cytokines), are the common cell-to-cell communication tool of the neuro-immuno-endocrine systems that regulate growth, repair, and renewal processes including apoptosis (cell death). Growth factors do not enter cells to modulate cellular activities via DNA expression. Growth factors convey their signals to highly specific cell receptors that in turn carry the message via a cascade of intracellular messengers into the DNA where gene transcription and expression are ultimately changed.
Specific growth factors, such as PDGF BB, IGF-1, hGH and TGFB1 play critical roles early in the G1 phase of the cell cycle where the cell's final behavior is determined. PDGF BB, IGF-1, and hGH support positive feedback to drive the cell cycle forward toward DNA synthesis and cell division, whereas TGFB1 provides negative feedback to induce cell death or 'hold position' signals depending upon environmental cues surrounding the cell, such as given by other neighboring cell signals.
Many viruses compete for the same DNA gene regulatory (transcription) sites as growth factors. Viruses must overcome the growth factor control of the cell's fate so that the virus can multiply and infect more cells.
Growth Factors provide Unique Information to Specific Cell Receptors.
Unless the molecule is identical to that which is produced in the body, no drug or supplement has specific receptors located in the outer cell membranes waiting for information to direct and balance the cell’s activities.
These growth factors tell cell receptors what the body needs. This includes:
When and how to let nutrients into the cell
When and what to eliminate as toxins
How to maximize energy
How to shift fuel metabolism for body repair and lean muscle building
How to restore homeostasis in the immune, nervous and immune systems
How to fight chronic viral infections
Plus hundreds of other essential bodily functions that lead to healing and better overall health.
The problem arises when the following interfere with optimal functioning of growth factors and cell receptors: viruses, such as measles
minute amounts of pollutants and toxins, such as mercury, lead and alcohol
trauma, excessive stimulation, or shocks, as can be caused by vaccines
Physiologically, as normally found in the body, some of the growth factors you find are:
Insulin-like Growth Factor-1 IGF-1
Platelet-derived Growth FactorBB PDGFBB
Transforming Growth Factor Beta-1 TGFB1
Granulocyte Macrophage Colony Stimulating Factor GMCSF
Fibroblast Growth Factor-2 FGF-2
Human Growth Hormone hGH
When not taken as drugs, (which would be very toxic), but at safe, homeopathic levels, the whole body responds in a balancing way because a non-molecular subtle energy support occurs throughout the body. As a new balance occurs, it is hypothesized that cell receptor sites may be signaled to better regulate healthy communications between the immune, nervous and endocrine systems. This new level of balance appears to help people with ASD function more appropriately in many new ways.
Cell-to-cell signaling with growth factors is the common language that coordinates these systems in the body. The communication between these systems is broken and interrupted during events which precipitate symptoms associated with autism as a result of physical or mental shock and trauma – caused by toxins, improperly administered vaccines, and disease. These cell signalers have many healing, repairing and instructive roles in the major defense systems of the body, thus offer a multitude of safe possibilities for use. |